Amitriptyline is occasionally used for bedwetting when alarms and desmopressin have not worked, but it requires careful clinical oversight. This article explains the evidence, side effects, safety considerations, and what to expect from treatment.
The British National Formulary sets out the prescribing options available for nocturnal enuresis in the UK, from desmopressin to amitriptyline. This article explains what each option does, when it’s used, and how NICE guidance shapes clinical decisions — helping parents engage more confidently with their child’s prescriber.
A number of common medications — including ADHD treatments, antipsychotics, and anticonvulsants — can cause or worsen bedwetting as a side effect. This article explains which drugs are most commonly implicated, the mechanisms involved, and how to raise the issue with your child’s prescribing clinician without stopping medication unsafely.
GPs have a small but well-evidenced toolkit for treating bedwetting in children. This guide explains each prescription option in plain English — what it does, who it suits, and what to realistically expect from treatment.
Imipramine has been used to treat bedwetting since the 1960s and remains a licensed option in the UK. This article explains how it works, what the evidence shows, and what parents need to know about safety and monitoring before starting treatment.